In lieu of an abstract, here is a brief excerpt of the content:Dialectic as "Philosophical Embarrassment":Heidegger's Critique of Plato's MethodFrancisco Gonzalez (bio)Philosophie ist ein Ringen um die Methode.(GA58, 228)Hans-Georg Gadamer has expressed the following debt to the thought of Martin Heidegger: "The philosophical stimuli I received from Heidegger led me more and more into the realm of dialectic, Plato's as well as Hegel's."1 It is therefore surprising to discover that Heidegger himself did not see his thought as leading him into (...) the realm of dialectic. On the contrary, in Being and Time we find a curt and unexplained dismissal of dialectic, specifically Plato's, as a "genuine philosophical embarrassment" (Verlegenheit).2 This dismissal is repeated in the Fundamental Concepts of Metaphysics course of WS 1929/30 where Heidegger asserts that "all dialectic in philosophy," and thus that of Hegel as well as Plato, "is only the expression of an embarrassment."3 Only with the publication of Heidegger's earlier lecture courses from the 1920s, are we in a position to understand and evaluate this surprising dismissal. We are also in a better position to understand why even the later Heidegger failed to reassess his rejection of dialectic, despite the existence of strong incentives for doing so: incentives recognized not only by Heidegger's students but, as will be shown, by Heidegger himself. What will emerge are not only the oft-observed limitations of Heidegger as an interpreter of Plato, but also, and more importantly, their source in certain limitations of Heidegger's own thinking. [End Page 361]1. Heidegger's Critique of Dialectic in the 1920sHeidegger's most detailed account of Plato's dialectic, and thus the one that best explains his curt dismissal of dialectic in later works, is to be found in the Sophist lectures of 1924/25.4 This account begins with a description of the pervasiveness and potential obstructiveness of. Though ordinarily and most immediately pervades all forms of disclosing (GA19, 196), "[a]ccording to its original sense and original facticity, is not at all disclosing (aufdeckend), but is, if one may speak in an extreme way, precisely concealing (verdeckend)" (197).5 In other words, is initially and for the most part "idle talk" (Gerede), the kind of speech that is bandied about concerning anything whatsoever and that "has the facticity of not allowing the things themselves to be seen, but producing instead a self-satisfaction in resting content with what 'one says'" (197). Thus speech at first presents itself as self-sufficient and autonomous; one hangs onto what is said without being directed beyond it to the things themselves.This tendency of to conceal is a theme to which Heidegger returns repeatedly in the courses of the 1920s. In a course from WS 1923/24 he argues that deception has its origin in the very facticity of language.6 In the unpublished course from SS 1924 ("Grundbegriffe der aristotelischen Philosophie"), the one that immediately preceded the Sophist lectures, Heidegger characterizes language as the proper domain of "Das Man" (18, 22) and describes the dominance of as leading to Gerede (7, 112).7 Heidegger therefore claims that because the Greeks lived in speech they were also imprisoned by it, with the result that a tremendous effort was needed for them to overcome their imprisonment and thus make science possible (41, 106 ).In the Sophist lectures, Heidegger assigns to dialectic an important role in this effort. Given both the pervasiveness and the concealing character of, philosophy, in its attempt to disclose the things themselves, must both begin with and break through it by means of a "speaking for and against" (Für- und Gegensprechen) that destroys the autonomy and self-sufficiency that has in Gerede and in this way "leads more and more to the matter under discussion and lets it be seen" (GA19, 197). What is needed, in short, is dia-lectic: a speaking that passes through speech.Already, however, one can see the tension that characterizes dialectic on Heidegger's account. Though dialectic is a, a speaking, it seeks to be more. Its aim is to disclose the things themselves of which it speaks, to see these things in a "pure seeing" uncontaminated by the... (shrink)

Platons Nomoi standen lange zu Unrecht im Schatten seiner Politeia. Dennoch prasentiert der umfangreiche und schwer zu interpretierende Dialog die Einsichten und Innovationen seines reifen Staatsdenkens. Sie werden in dem Band von internationalen Platon-Experten erschlossen. Zu diesen Einsichten und Innovationen zahlt der Gedanke, dass Machtmissbrauch durch politische Institutionen verhindert werden kann, und dass den Gesetzen Vorreden bzw. Praambeln vorangestellt werden sollen, die zu ihrer Befolgung uberreden. Die versammelten Original-Beitrage behandeln die zentralen Themen des Dialogs wie die neue Mischverfassung, die (...) politische Theologie, den Gesetzesbegriff, das Verhaltnis von Tugend- und Gesetzeslehre, die Erziehung und Bildung sowie den Einfluss und die Wirkung des Dialogs in der Antike, der Neuzeit und der Gegenwart. Eine ausfuhrliche Einleitung fuhrt in das Werk und seine Wirkungsgeschichte ein und informiert den Leser uber die Themen und Thesen der versammelten Beitrage. (shrink)

Delivery riders became frontline workers who assisted everyone in getting their daily supplies. They transported them to their destinations when the pandemic started, and everyone had to stay home to stop the COVID-19 virus from spreading. Thus, this study explores the experiences, challenges, and coping mechanisms of 15 Female Delivery Riders in Bulacan, Philippines. The study employed Heideggerian Phenomenology and Interpretative Phenomenological Analysis (IPA). Further, the following themes arise: (1) The Realist, (2) The Accommodated, (3) The Vulnerable, and (4) The (...) Determined. These themes highlighted the experiences and challenges faced by the participants. Moreover, it is highly suggested that female employees should be given preferential assistance given their physical capabilities and role in the family. Thus, local government units should provide an alternative source of income that will allow them to have quality time with their family, especially their children. (shrink)

ObjectiveTest anxiety (TA) is a construct that has scarcely been studied based on Lang’s three-dimensional model of anxiety. The objective of this article is to investigate the repercussion of sociodemographic and academic variables on different responses for each component of anxiety and for the type of test in adolescent students.MethodA total of 1181 students from 12 to 18 years old (M= 14.7 and SD = 1.8) participated, of whom 569 were boys (48.2%) and 612 girls (51.8%). A sociodemographic questionnaire and (...) theCuestionario de Ansiedad ante los examenes-Adaptado (CAEX-A)[Test Anxiety Questionnaire-Adapted] an adaptation for Spanish secondary school levels (ESO) and Bachillerato were administered.ResultsGirls scored higher on the cognitive and physiological components of TA than boys, the intensity of the physiological response increasing with age. Bachillerato level students reported more physiological anxiety than those of ESO level. Students with better marks in the previous year presented more anxiety in the cognitive component, while those who obtained the lower mark presented higher anxiety values in the behavioral component. Participants reported that the types of tests that cause them more anxiety were oral tests in front of the class, oral presentation in front of a panel, and mathematics tests.ConclusionAdolescents show a differential response of TA based on the physiological, cognitive and motor components, mediated by the variables of gender, age, grade, academic performance and type of exam. These results serve to design specific intervention programs to manage anxiety in situations of academic assessment. (shrink)

Silencing of tumor suppressor genes (TSGs), by DNA methylation, is well known in adult cancers. However, based on the “stem cell” theory of tumorigenesis, the early epigenetic events arising in malignant precursors remain unknown. A recent report1 demonstrates that, while pluripotent embryonic stem cells lack DNA methylation and possess a “bivalent” pattern of activating and repressive histone marks in numerous TSGs, analogous multipotent malignant cells derived from germ cell tumors (embryonic carcinoma cells) gain additional silencing modifications to those same genes. (...) These results suggest a possible mechanism by which aberrant differentiation, mediated by histone and DNA methylation, instigates tumor progression. BioEssays 29:842–845, 2007. © 2007 Wiley Periodicals, Inc. (shrink)

Graphical AbstractScience and technology consortia provide a viable solution for the recent unsustainable academic growth in biomedical research.

The failure of conventional quantum theory to recognize time as an observable and to admit time operators is addressed. Instead of focusing on the existence of a time operator for a given Hamiltonian, we emphasize the role of the Hamiltonian as the generator of translations in time to construct time states. Taken together, these states constitute what we call a timeline. Such timelines are adequate for the representation of any physical state, and appear to exist even for the semi-bounded and (...) discrete Hamiltonian systems ruled out by Pauli’s theorem. However, the step from a timeline to a valid time operator requires additional assumptions that are not always met. Still, this approach illuminates the issues surrounding the construction of time operators, and establishes timelines as legitimate alternatives to the familiar coordinate and momentum bases of standard quantum theory. (shrink)

Why do relationships of friendship and love support partiality, but not relationships of hatred or commitments of racism? Where does partiality end and why? I take the intuitive starting point that important cases of partiality are meaningful. I develop a view whereby meaning is understood in terms of transcending self-limitations in order to connect with things of external value. I then show how this view can be used to distinguish central cases of legitimate partiality from cases of illegitimate partiality and (...) how it puts pressure on the traditional way of thinking about partiality. (shrink)

Extinction deeply colors the way we think about conservation and the role of humans in nature. It is easy to overlook how recently, in fact, it has entered our consciousness. Only in the last two centuries has science sought to critically study life's origins, development, and diversification. Only in the last several generations have we identified and calibrated life's five major extinction events and speculated on their causes and effects. And only in recent decades have we come to appreciate the (...) still‐unfolding fate of life's diversity under the increasing influence of humanity. The story of extinction has continually changed as this monumental process of interdisciplinary synthesis and imagination has unfolded. Geology, paleontology, taxonomy, biogeography, and evolutionary biology have allowed us to comprehend the deep temporal and broad spatial dynamics of the extinction story. Archaeology, cultural anthropology, and environmental and economic history have illuminated the role of humans in altering the trajectory of species, landscapes, and ecosystems over the millennia. Ecology, genetics, population biology, and conservation biology have revealed the more recent patterns in life's vulnerability and resilience. As a phenomenon, extinction is as old as life itself. As a story shaping our consciousness, values, and intentions, it is still new. And it is uncomfortable. (shrink)

The ultimate source of explanation in biology is the principle of natural selection. Natural selection means differential reproduction of genes and gene combinations. It is a mechanistic process which accounts for the existence in living organisms of end-directed structures and processes. It is argued that teleological explanations in biology are not only acceptable but indeed indispensable. There are at least three categories of biological phenomena where teleological explanations are appropriate.

Autism Spectrum Disorder (ASD) is a neurodevelopmental condition characterized by social/communicative difficulties and perseverative behaviours. While research on autism has flourished recently, few studies have been conducted on the disorder in non‐Western contexts. In low‐ and middle‐income countries (LMICs), biomedical research on autism is required to better understand the needs of the population and to develop contextually appropriate interventions. However, autistic individuals are a vulnerable study population and LMICs present with various considerations. While the presentation of autism is heterogeneous, stigma (...) is a common social consequence affecting research. Drawing specifically on the South African context, the ethical intersections of these issues are discussed, along with the limitations of the current informed consent process. Community engagement is recommended as an adjunct to informed consent to ensure that biomedical research is conducted in a more inclusive way. Practical pointers are provided for implementing systematic support for conducting community engagement alongside biomedical research. (shrink)

A vital step to successfully orienting Deleuze with biosemiotics (and theories of biological complexity overall) is to discover a coherent scientific throughline in his work that also accounts for the aesthetic/creative dimension of his philosophy. This requires the heterodox move (from a Deleuzean point of view) of giving priority to the organism. I argue that Deleuze’s treatment of the organism does more than signal a superficial relation to biological complexity theory that, as a result of his nuanced take on the (...) matter, undermines the value of the organic body to his system. Instead, we can recognize a working theory of autopoiesis in the early Deleuze that scaffolds as well as substantiates his later ethological and biosemiotic observations and reveals a definite, albeit minimal, notion of subjectivity in his work. Most importantly, reorienting his logic of sense as a logic of sense-making, or the context-dependent signification between system and environment (Thompson, 2007), allows us to begin the work of mining a scientific throughline in Deleuze’s work akin to biological complexity theory that is of value to both Deleuze studies and biosemiotics. (shrink)

Die Autoren sind katholische Priester und stellen das christliche Menschenbild und die Ethik der Gesundheitssorge in den Mittelpunkt. Herausgearbeitet wird die ihrer Ansicht nach besondere ethische Verantwortung der Pflegekräfte in ihren Beziehungen zu Patienten, Angehörigen und Ärzten bei Fragen der Lebens- und Sterbehilfe.